Sumanth Ranganathan

 Establishment of a chemoenzymatic process (upstream and dwonstream) to synthesize monomers for bio-based polymers.  Design and development of robust analytics capable of high throughput operations.  Part of an international team studying the use of residual algal biomass as medium for biotransformations.  Fermentative production of microbial exopolysaccharides and chemical modification to study changes in properties

 Collaborated with Freaunhofer IGB to design and develop of a chemoenzymatic process to epoxidize terpenes.  Utilization of robust design techniques and design of experiments (DoE) to optimize the process in organic solvents and deep eutectic solvents  Implementation of the principles of green chemistry and scaling up of the process.  Process integration of the industrial hydrogen peroxide process and integration with the enzymatic one.

 Joined the start-up company as a bioorganic scientist to establish biocatalytic processes for fine chemicals.  Cloning, expression, and purification of recombinant enzymes needed for the enzymatic cascade.  Immobilization conditions of enzymes to enhance catalyst performance and enable simple recovery of the product.  Development of enzymatic assays to characterise enzymes of the process

• Research exchange period for extended process integration of anthraquinone hydrogen peroxide production with a chloroperoxidase enzyme for producing chlorinated hydrocarbons

• Developed an in vitro enzymatic cascade for 4 pentose phosphate pathway enzymes • Studied various production modes to combine the 4 enzymes • Produced and purified one of the enzymes of the cascade in a fed-batch mode in a 2L single-use fermenter • Characterized and investigated the inhibition and immobilization of the 4 enzymes

Process development, optimization and integration for the functionalization of fine and value added chemicals

Biocatalysis Unit Operations Chemical Reaction Engineering Technical Microbiology Bioprocess Engineering Downstream Operations Environmental Microbiology Heterogeneous Catalysis

Bioprocess Engineering Fermentation Microbiology Biopharmaceutical Technology Downstream Processing Chemical Reaction Engineering Unit Operations Environmental Biotechnology Heat & Mass Transfer